The Regional Offices of the DOST are mandated by law to:
- Identify S&T needs and opportunities in the region;
- Formulate a Regional S&T Plan;
- Plan and implement programs and projects on R&D and the delivery of S&T services;
- Monitor and coordinate programs and projects of DOST Councils, Institutes and Support Agencies in the region;
- Develop Institutional linkages; and
- Provide grants-in aid.